Dhe 45 Use Warnings

What may interact with DHE 45?

Do not take this medicine with any of the following medicines:
-clarithromycin
-cocaine
-conivaptan
-dexfenfluramine
-ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-ephedrine
-erythromycin
-feverfew
-grapefruit juice
-imatinib
-medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
-medicines used to treat colds or breathing difficulties
-medicines used to treat fungal infections like itraconazole, ketoconazole, posaconazole and voriconazole
-midodrine
-nefazodone
-nitrate medicines like nitroglycerin
-some medicines for HIV
-troleandomycin

This medicine may also interact with the following medications:
-medicines for blood pressure
-medicines for mental depression
-nicotine

What should I tell my health care provider before I take DHE 45?

They need to know if you have any of these conditions:
-blood vessel problems, or surgery on your arteries
-chest pain
-heart disease
-high blood pressure
-infection
-kidney disease
-liver disease
-risk factors for heart disease like smoking, high cholesterol, a family history of heart disease, or if you are a postmenopausal female or a male over 40 years of age
-an unusual or allergic reaction to dihydroergotamine, ergot alkaloids, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using DHE 45?

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light, moisture, and heat. Do not refrigerate or freeze. Throw away any unused medicine after the expiration date.