Amlodipine-Benazepril (Lotrel) Uses

The combination of amlodipine and benazepril is used to treat high blood pressure (hypertension) in people who have failed to achieve the desired antihypertensive effect on one of these medications alone or who developed edema (swelling) when taking amlodipine alone.

There may be other uses of amlodipine and benazepril—your pharmacist or doctor can give you further drug information.

Amlodipine-Benazepril (Lotrel) Mechanism of Action

Amlodipine is a calcium channel blocker and it widens blood vessels. Benazepril is an ACE inhibitor that blocks a chemical that tightens blood vessels. Together, the combination of amlodipine and benazepril improves blood flow and reduces the workload of the heart.

Amlodipine-Benazepril (Lotrel) Doses

The combination of amlodipine and benazepril is available in the following dosages:

• 2.5 mg amlodipine and 10 mg benazepril
• 5 mg amlodipine and 10 mg benazepril
• 5 mg amlodipine and 20 mg benazepril
• 5 mg amlodipine and 40 mg benazepril
• amlodipine 10 mg and benazepril 20 mg
• amlodipine 10 mg and benazepril 40 mg

The usual starting dose is amlodipine 2.5 mg and benazepril 10 mg once daily. If your blood pressure is not controlled after two weeks, your doctor may increase the dose up to 10 mg amlodipine and 40 mg benazepril once daily.